Transient exposure to sublethal concentrations of a pesticide mixture (chlorpyrifos–difenoconazole) caused different responses in fish species from different trophic levels of the same community
The assessment of early effects caused in biota by sublethal exposure to pesticide mixtures should enhance the realism in the ecological risk assessment for agricultural landscapes. This study aimed to evaluate sub-individual responses in fish, which can be linked with outcomes at higher levels of...
| Autores Principales: | Redondo, Sergei, León, Ana C., Jiménez, Katherine, Solano, Karla, Blanco-Peña, Kinndle, Mena, Freylan |
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| Formato: | Artículo |
| Idioma: | Inglés |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: |
http://hdl.handle.net/11056/24292 https://doi.org/10.1016/j.cbpc.2021.109208 |
| Sumario: |
The assessment of early effects caused in biota by sublethal exposure to pesticide mixtures should enhance the
realism in the ecological risk assessment for agricultural landscapes. This study aimed to evaluate sub-individual
responses in fish, which can be linked with outcomes at higher levels of biological organization and affect their
trophic relationships. A multilevel biomarker approach was applied to assess the effects of a 48 h exposure of two
freshwater mesoamerican fish species (Parachromis dovii and Poecilia gillii) to a mixture of sublethal concentra-
tions of chlorpyrifos (5 μg/L) and difenoconazole (325 μg/L). Transcriptomic induction of cyp1A and the ac-
tivities of 7-ethoxy-resorufin-O-distillase (EROD) and glutathione S-transferase (GST) were measured as
biotransformation-related biomarkers; cholinesterase activity (ChE) was assessed as a neurotoxicity biomarker;
resting metabolic rate (RMR) was measured as a physiological biomarker; and the movement of fish in a
dark–light environment as a behavior biomarker. The exposure to the mixture had evident effects on P. gillii, with
significant induction of cyp1A transcription, increased EROD activity, ChE inhibition in muscle, and increased
permanence in the light side of the dark–light environment. Meanwhile, P. dovii only showed significant in-
duction of cyp1A, without evidence of neurotoxicity or changes in behavior. This study demonstrates that the
severity of the effects caused by the exposure to a mixture of pesticides can differ among species from the same
trophic chain. The potential impairment of predator-prey relationships is a relevant effect that pesticide pollution
can cause and it should be considered for the risk assessment of such contaminants. |
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