A Biocomputational Platform for Template-based Protein-protein Docking

We propose the creation of a Biocomputational Platform for template-based protein-protein docking that aims reduce computational time by clustering data before the rigid body alignment. Using data from the Dockground project, models will be created using multiple clustering methods that will annotat...

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Autores Principales: Román-Brenes, Ricardo, Siles-Canales, Francisco, Zamora-Mata, Daniel
Formato: Artículo
Idioma: Inglés
Publicado: Editorial Tecnológica de Costa Rica (entidad editora) 2020
Materias:
HPC
Acceso en línea: https://revistas.tec.ac.cr/index.php/tec_marcha/article/view/5084
https://hdl.handle.net/2238/12077
Sumario: We propose the creation of a Biocomputational Platform for template-based protein-protein docking that aims reduce computational time by clustering data before the rigid body alignment. Using data from the Dockground project, models will be created using multiple clustering methods that will annotated each protein into a class, such that when performing the match search, not all of the databank needs to be inspected but just the class that resembles the most to the studied protein. This will reduce the time that conformation matching requires without incurring in lower precision.