The Combined Use of Alphavirus Replicons and Pseudoinfectious Particles for the Discovery of Antivirals Derived from Natural Products

por Delekta, Phillip C. , Raveh, Avi, Larsen, Martha J. , Schultz, Pamela J., Tamayo Castillo, Giselle, Sherman, David H., Miller, David J.
Publicado 2022

Adipostatins E-J, new potent antimicrobials identified as inhibitors of coenzyme-A biosynthesis

por Gómez Rodríguez, Lyanne, Schultz, Pamela J., Tamayo Castillo, Giselle, Dotson, Garry D., Sherman, David H., Tripathi, Ashootosh
Publicado 2021

Titration-Based Screening for Evaluation of Natural Product Extracts: Identification of an Aspulvinone Family of Luciferase Inhibitors

por Cruz, Patricia G. , Auld, Douglas S., Schultz, Pamela J., Lovell, Scott, Battaile, Kevin P., MacArthur, Ryan, Shen, Min , Tamayo Castillo, Giselle, Inglese, James, Sherman, David H.
Publicado 2022

Identification of Protein Kinase C Activation as a Novel Mechanism for RGS2 Protein Upregulation through Phenotypic Screening of Natural Product Extracts

por Raveh, Avi, Schultz, Pamela J., Aschermann, Lauren , Carpenter, Colleen, Tamayo Castillo, Giselle , Cao, Shugeng, Clardy, Jon, Neubig, Richard R., Sherman, David H., Sjögren, Benita
Publicado 2023

Novel Lobophorins Inhibit Oral Cancer Cell Growth and Induce Atf4- and Chop-Dependent Cell Death in Murine Fibroblasts

por Cruz, Patricia G., Fribley, Andrew M., Miller, Justin R., Larsen, Martha J., Schultz, Pamela J., Jacob, Renju T., Tamayo Castillo, Giselle, Kaufman, Randal J., Sherman, David H.
Publicado 2019

Discovery of nicoyamycin A, an inhibitor of uropathogenic Escherichia coli growth in low iron environments

por Mike, Laura A., Tripathi, Ashootosh, Blankenship, Connor M., Saluk, Alyssa, Schultz, Pamela J., Tamayo Castillo, Giselle, Sherman, David H., Mobley, Harry L. T.
Publicado 2020

Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway

por Park, Sung Ryeol, Tripathi, Ashootosh, Wu, Jianfeng, Schultz, Pamela J., Yim, Isaiah, McQuade, Thomas J., Yu, Fengan, Arevang, Carl Johan, Mensah, Abraham Y., Tamayo Castillo, Giselle, Xi, Chuanwu, Sherman, David H.
Publicado 2018

Baulamycins A and B, Broad-Spectrum Antibiotics Identified as Inhibitors of Siderophore Biosynthesis in Staphylococcus aureus and Bacillus anthracis

por Tripathi, Ashootosh, Schofield, Michael M., Chlipala, George E., Schultz, Pamela J., Yim, Isaiah, Newmister, Sean A., Nusca, Tyler D., Scaglione, Jamie B., Hanna, Philip C., Tamayo Castillo, Giselle, Sherman, David H.
Publicado 2023

Uncovering the Cultivable Microbial Diversity of Costa Rican Beetles and Its Ability to Break Down Plant Cell Wall Components

por Vargas Asensio, Juan Gabriel, Pinto Tomás, Adrián A., Rivera Vargas, Beatriz, Hernández Alfaro, Myriam, Hernández Herrero, Carlos, Soto Montero, Silvia, Murillo Cruz, Catalina, Sherman, David H., Tamayo Castillo, Giselle
Publicado 2023

Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product Extracts

por Cheng, Ken Chih-Chien, Cao, Shugeng, Raveh, Avi, MacArthur, Ryan, Dranchak, Patricia, Chlipala, George E., Okoneski, Matthew T., Guha, Rajarshi, Eastman, Richard T., Yuan, Jing, Schultz, Pamela J., Su, Xin-zhuan, Tamayo Castillo, Giselle, Matainaho, Teatulohi, Clardy, Jon, Sherman, David H., Inglese, James
Publicado 2018

Sekikaic Acid and Lobaric Acid Target a Dynamic Interface of the Coactivator CBP/p300

por Majmudar, Chinmay Y., Højfeldt, Jonas W., Arevang, Carl J., Pomerantz, William C., Gagnon, Jessica K., Schultz, Pamela J., Cesa, Laura C., Doss, Conor H., Rowe, Steven P., Vásquez Chaves, Víctor, Tamayo Castillo, Giselle, Cierpicki, Tomasz, Brooks, Charles L. III, Sherman, David H., Mapp, Anna K.
Publicado 2023

Borrelidin Induces the Unfolded Protein Response in Oral Cancer Cells and Chop-Dependent Apoptosis

por Sidhu, Alpa, Miller, Justin R., Tripathi, Ashootosh, Garshott, Danielle M., Brownell, Amy L., Chiego, Daniel J., Arevang, Carl Johan, Zeng, Qinghua, Jackson, Leah C., Bechler, Shelby A., Callaghan, Michael U., Yoo, George H., Sethi, Seema, Lin, Ho-Sheng, Callaghan, Joseph H., Tamayo Castillo, Giselle, Sherman, David H., Kaufman, Randal J., Fribley, Andrew M.
Publicado 2019