Vista Equipo: Characterization and applications of silver nanoparticles-decorated electrospun nanofibers loaded with polyphenolic extract from rambutan (Nepelium lappaceum)

Characterization and applications of silver nanoparticles-decorated electrospun nanofibers loaded with polyphenolic extract from rambutan (Nepelium lappaceum)

Rambutan (Nephelium lappaceum) is a traditional fruit originally from Asia and now widely available in Central America. The rind of rambutan is rich in antioxidants, especially polyphenols, which have natural anti-inflammatory and antimicrobial properties. Rambutan polyphenolic extract (RPE) was enc...

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Autores Principales:	Urena-Saborio, Hilary, Rodríguez, Gerardo, Madrigal-Carballo, Sergio, Gunasekaran, Sundaram
Formato:	Artículo
Idioma:	Inglés
Publicado:	Elsevier B.V. 2021
Materias:	ANTIBACTERIAL ANTIOXIDANT BIOACTIVE ELECTROSPUN MEMBRANE NANOPARTICLES SCAFFOLDS NANOPARTÍCULAS ANTIOXIDANTE
Acceso en línea:	http://hdl.handle.net/11056/22254

id	RepoUNACR22254
recordtype	dspace
spelling	RepoUNACR222542021-12-03T16:32:08Z Characterization and applications of silver nanoparticles-decorated electrospun nanofibers loaded with polyphenolic extract from rambutan (Nepelium lappaceum) Urena-Saborio, Hilary Rodríguez, Gerardo Madrigal-Carballo, Sergio Gunasekaran, Sundaram ANTIBACTERIAL ANTIOXIDANT BIOACTIVE ELECTROSPUN MEMBRANE NANOPARTICLES SCAFFOLDS NANOPARTÍCULAS ANTIOXIDANTE Rambutan (Nephelium lappaceum) is a traditional fruit originally from Asia and now widely available in Central America. The rind of rambutan is rich in antioxidants, especially polyphenols, which have natural anti-inflammatory and antimicrobial properties. Rambutan polyphenolic extract (RPE) was encapsulated in multi-component electrospun nanofiber (ESNF) templates. These nanofibers were decorated with silver nanoparticles (AgNPs) via in situ electrochemical reduction. The RPE-loaded and AgNPs-decorated ESNF (AgNPs/RPE-ESNF) were evaluated for their hydrophilic, antioxidant, and antimicrobial properties. Results indicate that the addition of RPE to synthetic polycaprolactone (PCL) ESNF improves hydrophilicity and cell attachment and proliferation in vitro. In addition, a synergistic antibacterial and cell proliferation effect between AgNPs and RPE was observed when they were combined in the multi-functionalized ESNF system. The effectiveness of AgNPs/RPE-PCL ESNF as an antioxidant and antibacterial matrix could potentially promote wound healing and also serve as a hybrid scaffold for tissue engineering. El rambután (Nephelium lappaceum) es una fruta tradicional originaria de Asia y ahora ampliamente disponible en América Central. La corteza del rambután es rica en antioxidantes, especialmente polifenoles, que tienen propiedades antiinflamatorias y antimicrobianas naturales. El extracto polifenólico de rambután (RPE) se encapsuló en plantillas de nanofibras electrohiladas (ESNF) multicomponente. Estas nanofibras se decoraron con nanopartículas de plata (AgNP) mediante reducción electroquímica in situ. Los ESNF cargados con RPE y decorado con AgNP (AgNPs / RPE-ESNF) se evaluaron por sus propiedades hidrófilas, antioxidantes y antimicrobianas. Los resultados indican que la adición de RPE a policaprolactona sintética (PCL) ESNF mejora la hidrofilia y la unión y proliferación celular in vitro. Además, se observó un efecto sinérgico antibacteriano y de proliferación celular entre los AgNP y el RPE cuando se combinaron en el sistema ESNF multifuncionalizado. La eficacia de AgNPs / RPE-PCL ESNF como matriz antioxidante y antibacteriana podría promover la cicatrización de heridas y también servir como un andamio híbrido para la ingeniería de tejidos. Universidad Nacional, Costa Rica University of Wisconsin-Madison, United States Escuela de Química 2021-12-03T16:32:07Z 2021-12-03T16:32:07Z 2020-05 http://purl.org/coar/resource_type/c_6501 25891529 http://hdl.handle.net/11056/22254 10.1016/j.mtla.2020.100687 eng Acceso embargado application/pdf Elsevier B.V. Materialia Vol 11. 2020
institution	Universidad Nacional de Costa Rica
collection	Repositorio UNA-Costa Rica
language	Inglés
topic	ANTIBACTERIAL ANTIOXIDANT BIOACTIVE ELECTROSPUN MEMBRANE NANOPARTICLES SCAFFOLDS NANOPARTÍCULAS ANTIOXIDANTE
spellingShingle	ANTIBACTERIAL ANTIOXIDANT BIOACTIVE ELECTROSPUN MEMBRANE NANOPARTICLES SCAFFOLDS NANOPARTÍCULAS ANTIOXIDANTE Urena-Saborio, Hilary Rodríguez, Gerardo Madrigal-Carballo, Sergio Gunasekaran, Sundaram Characterization and applications of silver nanoparticles-decorated electrospun nanofibers loaded with polyphenolic extract from rambutan (Nepelium lappaceum)
description	Rambutan (Nephelium lappaceum) is a traditional fruit originally from Asia and now widely available in Central America. The rind of rambutan is rich in antioxidants, especially polyphenols, which have natural anti-inflammatory and antimicrobial properties. Rambutan polyphenolic extract (RPE) was encapsulated in multi-component electrospun nanofiber (ESNF) templates. These nanofibers were decorated with silver nanoparticles (AgNPs) via in situ electrochemical reduction. The RPE-loaded and AgNPs-decorated ESNF (AgNPs/RPE-ESNF) were evaluated for their hydrophilic, antioxidant, and antimicrobial properties. Results indicate that the addition of RPE to synthetic polycaprolactone (PCL) ESNF improves hydrophilicity and cell attachment and proliferation in vitro. In addition, a synergistic antibacterial and cell proliferation effect between AgNPs and RPE was observed when they were combined in the multi-functionalized ESNF system. The effectiveness of AgNPs/RPE-PCL ESNF as an antioxidant and antibacterial matrix could potentially promote wound healing and also serve as a hybrid scaffold for tissue engineering.
format	Artículo
author	Urena-Saborio, Hilary Rodríguez, Gerardo Madrigal-Carballo, Sergio Gunasekaran, Sundaram
author_sort	Urena-Saborio, Hilary
title	Characterization and applications of silver nanoparticles-decorated electrospun nanofibers loaded with polyphenolic extract from rambutan (Nepelium lappaceum)
title_short	Characterization and applications of silver nanoparticles-decorated electrospun nanofibers loaded with polyphenolic extract from rambutan (Nepelium lappaceum)
title_full	Characterization and applications of silver nanoparticles-decorated electrospun nanofibers loaded with polyphenolic extract from rambutan (Nepelium lappaceum)
title_fullStr	Characterization and applications of silver nanoparticles-decorated electrospun nanofibers loaded with polyphenolic extract from rambutan (Nepelium lappaceum)
title_full_unstemmed	Characterization and applications of silver nanoparticles-decorated electrospun nanofibers loaded with polyphenolic extract from rambutan (Nepelium lappaceum)
title_sort	characterization and applications of silver nanoparticles-decorated electrospun nanofibers loaded with polyphenolic extract from rambutan (nepelium lappaceum)
publisher	Elsevier B.V.
publishDate	2021
url	http://hdl.handle.net/11056/22254
_version_	1796096718256734208
score	12.239212

Characterization and applications of silver nanoparticles-decorated electrospun nanofibers loaded with polyphenolic extract from rambutan (Nepelium lappaceum)

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