A bvrR/bvrS Non-Polar Brucella abortus Mutant Confirms the Role of the Two-Component System BvrR/BvrS in Virulence and Membrane Integrity

por Rivas-Solano, Olga, Núñez-Montero, Kattia, Altamirano-Silva, Pamela, Ruiz-Villalobos, Nazareth, BARQUERO-CALVO, ELIAS, Moreno, Edgardo, Chaves-Olarte, Esteban, Guzman-Verri, Caterina
Publicado 2023

BvrR/BvrS-controlled outer membrane proteins Omp3a and Omp3b are not essential for Brucella abortus virulence

por Manterola, Lorea, Guzman-Verri, Caterina, Chaves-Olarte, Esteban, BARQUERO-CALVO, ELIAS, de Miguel, María-Jesús, Moriyon, Ignacio, Grillo, María-Jesús, López-Goñi, Ignacio, Moreno, Edgardo
Publicado 2020

Brucellosis caused by the wood rat pathogen Brucella Neotomae: two case reports

por Arnuy, Ernesto, Rojas, Norman, Villalobos-Vindas, Juan M., BARQUERO-CALVO, ELIAS, Chacón-Díaz, Carlos, Chaves-Olarte, Esteban, Guzman-Verri, Caterina, Moreno, Edgardo
Publicado 2020

Epidemiology of bovine brucellosis in Costa Rica: Lessons learned from failures in the control of the disease

por Hernández Mora, Gabriela, Ruiz Villalobos, Nazareth, Bonilla Montoya, Roberto, Romero Zúñiga, Juan José, Jiménez Arias, Julio, González Barrientos, Rocío, Barquero Calvo, Elías, Chacón Díaz, Carlos, Rojas Campos, Norman, Chaves Olarte, Esteban, Guzmán Verri, Caterina, Moreno Robles, Edgardo
Publicado 2023

Brucella abortus Induces the Premature Death of Human Neutrophils through the Action of Its Lipopolysaccharide

por Barquero Calvo, Elías, Mora Cartín, Ricardo, Arce Gorvel, Vilma, de Diego, Juana L., Chacón Díaz, Carlos, Chaves Olarte, Esteban, Guzmán Verri, Caterina, Buret, Andre G., Gorvel, Jean Pierre, Moreno Robles, Edgardo
Publicado 2019

A Clostridium difficile Lineage Endemic to Costa Rican Hospitals Is Multidrug Resistant by Acquisition of Chromosomal Mutations and Novel Mobile Genetic Elements

por Ramírez Vargas, Gabriel, Quesada Gómez, Carlos, Acuña Amador, Luis Alberto, López Ureña, Diana, Murillo Corrales, Tatiana, Gamboa Coronado, María del Mar, Chaves Olarte, Esteban, Thomson, Nicholas R., Rodríguez Cavallini, Evelyn, Rodríguez Sánchez, César
Publicado 2018

Brucella neotomae Infection in Humans, Costa Rica

por Suárez Esquivel, Marcela, Ruiz Villalobos, Nazareth, Jiménez Rojas, César, Barquero Calvo, Elías, Chacón Díaz, Carlos, Víquez Ruiz, Eunice, Rojas Campos, Norman, Baker, Kate S., Oviedo Sánchez, Gerardo, Amuy, Ernesto, Chaves Olarte, Esteban, Thomson, Nicholas R., Moreno Robles, Edgardo, Guzmán Verri, Caterina
Publicado 2023

Brucella Genetic Variability in Wildlife Marine Mammals Populations Relates to Host Preference and Ocean Distribution

por Suárez Esquivel, Marcela, Baker, Kate S., Ruiz Villalobos, Nazareth, Hernández Mora, Gabriela, Barquero Calvo, Elías, Castillo Zeledón, Amanda, Jiménez Rojas, César, Chacón Díaz, Carlos, Cloeckaert, Axel, Chaves Olarte, Esteban, Thomson, Nicholas R., Moreno Robles, Edgardo, Guzmán Verri, Caterina, González Barrientos, Rocío
Publicado 2020

Brucella canis Is an Intracellular Pathogen That Induces a Lower Proinflammatory Response than Smooth Zoonotic Counterparts

por Chacón Díaz, Carlos, Altamirano Silva, Pamela, González Espinoza, Gabriela, Medina, María Concepción, Alfaro Alarcón, Alejandro, Bouza Mora, Laura, Jiménez Rojas, César, Wong Araya, Melissa, Barquero Calvo, Elías, Rojas Campos, Norman, Guzmán Verri, Caterina, Moreno Robles, Edgardo, Chaves Olarte, Esteban
Publicado 2019

Phenotypes controlled by the Brucella abortus two component system BvrR/BvrS are differentially impacted by BvrR phosphorylation

por Altamirano Silva, Pamela, Meza Torres, Jazmín Andrea, Zúñiga Pereira, Ana Mariel, Zamora Jaen, Sigrid, Pietrosemoli, Natalia, Cantos González, Gabriela, Peltier, Johann, Pizarro Cerdá, Javier, Moreno Robles, Edgardo, Chacón Díaz, Carlos, Guzmán Verri, Caterina, Chaves Olarte, Esteban
Publicado 2023

Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities

por Quesada Gómez, Carlos, López Ureña, Diana, Chumbler, Nicole, Kroh, Heather K., Castro Peña, Carolina, Rodríguez Sánchez, César, Orozco Aguilar, Josué, González Camacho, Sara María, Rucavado Romero, Alexandra, Guzmán Verri, Caterina, Lawley, Trevor D., Lacy, D. Borden, Chaves Olarte, Esteban
Publicado 2017

Senses the Intracellular Environment through the BvrR/BvrS Two-Component System, Which Allows To Adapt to Its Replicative Niche

por Altamirano Silva, Pamela, Meza Torres, Jazmín Andrea, Castillo Zeledón, Amanda, Ruiz Villalobos, Nazareth, Zúñiga Pereira, Ana Mariel, Chacón Díaz, Carlos, Moreno Robles, Edgardo, Guzmán Verri, Caterina, Chaves Olarte, Esteban
Publicado 2019

Novel Clade C-I Clostridium difficile strains escape diagnostic tests, differ in pathogenicity potential and carry toxins on extrachromosomal elements

por Ramírez Vargas, Gabriel, López Ureña, Diana, Badilla Lobo, Adriana, Orozco Aguilar, Josué, Murillo Corrales, Tatiana, Rojas, Priscilla, Riedel, Thomas, Overmann, Jörg, González, Gabriel, Chaves Olarte, Esteban, Quesada Gómez, Carlos, Rodríguez Sánchez, César
Publicado 2018

Toxin B Variants from Clostridium difficile Strains VPI 10463 and NAP1/027 Share Similar Substrate Profile and Cellular Intoxication Kinetics but Use Different Host Cell Entry Fact...

por López Ureña, Diana, Orozco Aguilar, Josué, Chaves Madrigal, Yendry Pamela, Ramírez Mata, Andrea, Villalobos Jimenez, Amanda, Ost, Stefan, Quesada Gómez, Carlos, Rodríguez Sánchez, César, Papatheodorou, Panagiotis, Chaves Olarte, Esteban
Publicado 2020

Proteogenomic analysis of the Clostridium difficile exoproteome reveals a correlation between phylogenetic distribution and virulence potential

por Quesada Gómez, Carlos, Murillo Corrales, Tatiana, Arce, Grettel, Badilla Lobo, Adriana, Castro Peña, Carolina, Molina Mora, José Arturo, López Ureña, Diana, González Camacho, Sara María, Lomonte, Bruno, Chacón Díaz, Carlos, Rodríguez Sánchez, César, Chaves Olarte, Esteban
Publicado 2021

Persistence of Brucella abortus lineages revealed by genomic characterization and phylodynamic analysis

por Suárez-Esquivel, Marcela, Henández-Mora, Gabriela, Ruiz-Villalobos, Nazareth, BARQUERO-CALVO, ELIAS, Chacón-Díaz, Carlos, LadnerI, JasonT., Oviedo-Sánchez, Gerardo, Foster, JeffreyT., Rojas-Campos, Norman, Chaves-Olarte, Esteban, Thomson, Nicholas, Moreno, Edgardo, Guzman-Verri, Caterina
Publicado 2020

Brucella genetic variability in wildlife marine mammals populations relates to host preference and ocean distribution

por Suárez-Esquivel, Marcela, Baker, Kate, Ruiz-Villalobos, Nazareth, Hernandez-Mora, Gabriela, BARQUERO-CALVO, ELIAS, González-Barrientos, Rocío, Castillo-Zeledón, Amanda, Jiménez-Rojas, César, Chacón-Díaz, Carlos, Cloeckaert, Axel, Chaves-Olarte, Esteban, Thomson, Nicholas, Moreno, Edgardo, Guzman-Verri, Caterina
Publicado 2020

Brucella abortus ornithine lipids are dispensable outer membrane components devoid of a marked pathogen-associated molecular pattern

por Palacios-Chaves, Leyre, Conde-Álvarez, Raquel, Gil-Ramírez, Yolanda, Zúñiga-Ripa, Amaia, BARQUERO-CALVO, ELIAS, Chacón-Díaz, Carlos, Chaves-Olarte, Esteban, Arce-Gorvel, Vilma, Gorvel, Jean-Pierre, Moreno, Edgardo, de Miguel, María-Jesús, Grilló, María-Jesús, Moriyon, Ignacio, Iriarte, Maite
Publicado 2020

The differential interaction of brucella and ochrobactrum with innate immunity reveals traits related to the evolution of stealthy pathogens

por BARQUERO-CALVO, ELIAS, Conde-Álvarez, Raquel, Chacón-Díaz, Carlos, Quesada-Lobo, LucÍa, Martirosyan, Anna, Guzman-Verri, Caterina, Iriarte, Maite, Manček Keber, Mateja, Jerala, Roman, Gorvel, Jean-Pierre, Moriyon, Ignacio, Moreno, Edgardo, Chaves-Olarte, Esteban
Publicado 2020

Brucella neotomae infection in humans, Costa Rica

por BARQUERO-CALVO, ELIAS, Baker, Kate S., Amuy, Ernesto, Chaves-Olarte, Esteban, Thomson, Nicholas R., Moreno, Edgardo, Guzman-Verri, Caterina, Suárez-Esquivel, Marcela, Ruiz-Villalobos, Nazareth, Jiménez-Rojas, César, Chacón-Díaz, Carlos, Víquez-Ruiz, Eunice, Rojas-Campos, Norman, Oviedo-Sánchez, Gerardo
Publicado 2020