Freeze-dried snake antivenoms formulated with sorbitol, sucrose or mannitol: Comparison of their stability in an accelerated test

por Herrera Vega, María, Tattini Jr., Virgilio, Pitombo, Ronaldo N. M., Gutiérrez, José María, Borgognoni, Camila, Vega Baudrit, José, Solera, Federico, Cerdas Solís, Maykel, Segura Ruiz, Álvaro, Villalta Arrieta, Mauren, Villalta Arrieta, Mauren, Vargas Arroyo, Mariángela, León Montero, Guillermo
Publicado 2017

Pathogenic mechanisms underlying adverse reactions induced by intravenous administration of snake antivenoms

por León Montero, Guillermo, Herrera Vega, María, Segura Ruiz, Álvaro, Villalta Arrieta, Mauren, Vargas Arroyo, Mariángela, Gutiérrez, José María
Publicado 2017

Pathogenesis of dermonecrosis induced by venom of the spitting cobra, Naja nigricollis: An experimental study in mice

por Rivel Piedra, Mario, Solano, Daniela, Herrera Vega, María, Vargas Arroyo, Mariángela, Villalta Arrieta, Mauren, Segura Ruiz, Álvaro
Publicado 2017

Purification of equine whole IgG snake antivenom by using an aqueous two phase system as a primary purification step

por Vargas Arroyo, Mariángela, Segura Ruiz, Álvaro, Villalta Arrieta, Mauren, Herrera Vega, María, Gutiérrez, José María, León Montero, Guillermo
Publicado 2017

Immune Response Towards Snake Venoms

por León Montero, Guillermo, Sánchez Céspedes, Laura Vanessa, Hernández, Andrés, Villalta Arrieta, Mauren, Herrera Vega, María, Segura Ruiz, Álvaro, Estrada Umaña, Ricardo, Gutiérrez, José María
Publicado 2017

Effect of geographical variation of Echis ocellatus, Naja nigricollis and Bitis arietans venoms on their neutralization by homologous and heterologous antivenoms

por Sánchez Brenes, Andrés, Coto Porras, Jorge, Segura Ruiz, Álvaro, Vargas Arroyo, Mariángela, Solano Trejos, María Gabriela, Herrera Vega, María, Villalta Arrieta, Mauren, Estrada Umaña, Ricardo, Gutiérrez, José María
Publicado 2017

Efficacy of IgG and F(ab′)2 Antivenoms to Neutralize Snake Venom-induced Local Tissue Damage as Assessed by the Proteomic Analysis of Wound Exudate

por Rucavado Romero, Alexandra, Escalante Muñoz, Teresa, Shannon, John D., Ayala Castro, Carla N., Villalta Arrieta, Mauren, Gutiérrez, José María, Fox, Jay W.
Publicado 2017

Study of the design and analytical properties of the lethality neutralization assay used to estimate antivenom potency against Bothrops asper snake venom

por Solano Trejos, María Gabriela, Segura Ruiz, Álvaro, Herrera Vega, María, Gómez Argüello, Aarón, Villalta Arrieta, Mauren, Gutiérrez, José María, León Montero, Guillermo
Publicado 2016

Toxicity of Bothrops sp snake venoms from Ecuador and preclinical assessment of the neutralizing efficacy of a polyspecific antivenom from Costa Rica

por Laines, Johana, Segura Ruiz, Álvaro, Villalta Arrieta, Mauren, Herrera Vega, María, Vargas Arroyo, Mariángela, Alvarez, Gladys, Gutiérrez, José María, León Montero, Guillermo
Publicado 2017

Lachesis stenophrys venom reduces the equine antibody response towards Bothrops asper venom used as co-immunogen in the production of polyspecific snake antivenom

por Arroyo Portilla, Cynthia, Solano Rojas, Sergio, Herrera Vega, María, Segura Ruiz, Álvaro, Estrada Umaña, Ricardo, Vargas Arroyo, Mariángela, Villalta Arrieta, Mauren, León Montero, Guillermo
Publicado 2017

Purification of IgG and albumin from human plasma by aqueous two phase system fractionation

por Vargas Arroyo, Mariángela, Segura Ruiz, Álvaro, Herrera Vega, María, Villalta Arrieta, Mauren, Angulo Ugalde, Yamileth, Gutiérrez, José María, León Montero, Guillermo
Publicado 2017

Comparison of the effect of Crotalus simus and Crotalus durissus ruruima venoms on the equine antibody response towards Bothrops asper venom: Implications for the production of pol...

por Dos Santos, María Cristina, Arroyo Portilla, Cynthia, Solano Rojas, Sergio, Herrera Vega, María, Villalta Arrieta, Mauren, Segura Ruiz, Álvaro, Estrada Umaña, Ricardo, Gutiérrez, José María, León Montero, Guillermo
Publicado 2017

Preclinical evaluation of the efficacy of antivenoms for snakebite envenoming: State-of-the-art and challenges ahead

por Solano Trejos, María Gabriela, Pla Ferrer, Davinia, Herrera Vega, María, Segura Ruiz, Álvaro, Vargas Arroyo, Mariángela, Villalta Arrieta, Mauren, Sánchez Brenes, Andrés, Sanz, Libia, Lomonte, Bruno, León Montero, Guillermo, Calvete Chornet, Juan José, Gutiérrez, José María
Publicado 2018

Comparison of the adjuvant activity of aluminum hydroxide and calcium phosphate on the antibody response towards Bothrops asper snake venom

por Olmedo, Hidekel, Herrera Vega, María, Rojas Sánchez, Leonardo, Villalta Arrieta, Mauren, Vargas Arroyo, Mariángela, Leiguez, Elbio, Teixeira, Catarina de Fátima, Estrada Umaña, Ricardo, Gutiérrez, José María, León Montero, Guillermo, Montero Villalobos, Mavis Lili
Publicado 2017

Preclinical evaluation of caprylic-acid fractionated IgG antivenom for the treatment of taipan (Oxyuranus scutellatus) envneoming in Papua New Guinea

por Vargas Arroyo, Mariángela, Segura Ruiz, Álvaro, Herrera Vega, María, Villalta Arrieta, Mauren, Estrada Umaña, Ricardo, Cerdas Solís, Maykel, Paiva, Owen K., Matainaho, Teatulohi, Jensen, Simon D., Winkel, Kenneth D., León Montero, Guillermo, Gutiérrez, José María, Williams, David J.
Publicado 2014

Role of the animal model on the pharmacokinetics of equine-derived antivenoms

por Rojas Araya, Alicia, Vargas Arroyo, Mariángela, Ramírez Arguedas, Nils Antonio, Estrada Umaña, Ricardo, Segura Ruiz, Álvaro, Herrera Vega, María, Villalta Arrieta, Mauren, Gómez Argüello, Aarón, Gutiérrez, José María, León Montero, Guillermo
Publicado 2017

Antivenomic Assessment of the Immunological Reactivity of EchiTAb-Plus-ICP, an Antivenom for the Treatment of Snakebite Envenoming in Sub-Saharan Africa

por Calvete Chornet, Juan José, Cid, Pedro, Sanz, Libia, Segura Ruiz, Álvaro, Villalta Arrieta, Mauren, Herrera Vega, María, León Montero, Guillermo, Harrison, Robert A., Durfa, Nandul, Nasidi, Abdulsalami, Theakston, R. David G., Warrell, David A., Gutiérrez, José María
Publicado 2016

Development of a chicken-derived antivenom against the taipan snake (Oxyuranus scutellatus) venom and comparison with an equine antivenom

por Navarro, Diego Arias, Vargas Arroyo, Mariángela, Herrera Vega, María, Segura Ruiz, Álvaro, Gómez Argüello, Aarón, Villalta Arrieta, Mauren, Ramírez Arguedas, Nils Antonio, Williams, David J., Gutiérrez, José María, León Montero, Guillermo
Publicado 2017

Preclinical assessment of the efficacy of a new antivenom (EchiTAb-Plus-ICP) for the treatment of viper envenoming in sub-Saharan Africa

por Segura Ruiz, Álvaro, Villalta Arrieta, Mauren, Herrera Vega, María, León Montero, Guillermo, Harrison, Robert A., Durfa, Nandul, Nasidi, Abdulsalami, Calvete Chornet, Juan José, Theakston, R. David G., Warrell, David A., Gutiérrez, José María
Publicado 2016

Assessing the preclinical efficacy of antivenoms: From the lethality neutralization assay to antivenomics

por Gutiérrez, José María, Solano Trejos, María Gabriela, Pla Ferrer, Davinia, Herrera Vega, María, Segura Ruiz, Álvaro, Villalta Arrieta, Mauren, Vargas Arroyo, Mariángela, Sanz, Libia, Lomonte, Bruno, Calvete Chornet, Juan José, León Montero, Guillermo
Publicado 2017