Pathogenic mechanisms underlying adverse reactions induced by intravenous administration of snake antivenoms

by León Montero, Guillermo, Herrera Vega, María, Segura Ruiz, Álvaro, Villalta Arrieta, Mauren, Vargas Arroyo, Mariángela, Gutiérrez, José María
Published 2017

Purification of equine whole IgG snake antivenom by using an aqueous two phase system as a primary purification step

by Vargas Arroyo, Mariángela, Segura Ruiz, Álvaro, Villalta Arrieta, Mauren, Herrera Vega, María, Gutiérrez, José María, León Montero, Guillermo
Published 2017

Pathogenesis of dermonecrosis induced by venom of the spitting cobra, Naja nigricollis: An experimental study in mice

by Rivel Piedra, Mario, Solano, Daniela, Herrera Vega, María, Vargas Arroyo, Mariángela, Villalta Arrieta, Mauren, Segura Ruiz, Álvaro
Published 2017

Study of the design and analytical properties of the lethality neutralization assay used to estimate antivenom potency against Bothrops asper snake venom

by Solano Trejos, María Gabriela, Segura Ruiz, Álvaro, Herrera Vega, María, Gómez Argüello, Aarón, Villalta Arrieta, Mauren, Gutiérrez, José María, León Montero, Guillermo
Published 2016

Immune Response Towards Snake Venoms

by León Montero, Guillermo, Sánchez Céspedes, Laura Vanessa, Hernández, Andrés, Villalta Arrieta, Mauren, Herrera Vega, María, Segura Ruiz, Álvaro, Estrada Umaña, Ricardo, Gutiérrez, José María
Published 2017

Industrial Production and Quality Control of Snake Antivenoms

by León Montero, Guillermo, Segura Ruiz, Álvaro, Gómez Argüello, Aarón, Hernández Bolaños, Andrés, Navarro Arias, Diego, Villalta Arrieta, Mauren, Vargas Arroyo, Mariángela, Herrera Vega, María, Gutiérrez, José María
Published 2019

Lachesis stenophrys venom reduces the equine antibody response towards Bothrops asper venom used as co-immunogen in the production of polyspecific snake antivenom

by Arroyo Portilla, Cynthia, Solano Rojas, Sergio, Herrera Vega, María, Segura Ruiz, Álvaro, Estrada Umaña, Ricardo, Vargas Arroyo, Mariángela, Villalta Arrieta, Mauren, León Montero, Guillermo
Published 2017

Purification of IgG and albumin from human plasma by aqueous two phase system fractionation

by Vargas Arroyo, Mariángela, Segura Ruiz, Álvaro, Herrera Vega, María, Villalta Arrieta, Mauren, Angulo Ugalde, Yamileth, Gutiérrez, José María, León Montero, Guillermo
Published 2017

Toxicity of Bothrops sp snake venoms from Ecuador and preclinical assessment of the neutralizing efficacy of a polyspecific antivenom from Costa Rica

by Laines, Johana, Segura Ruiz, Álvaro, Villalta Arrieta, Mauren, Herrera Vega, María, Vargas Arroyo, Mariángela, Alvarez, Gladys, Gutiérrez, José María, León Montero, Guillermo
Published 2017

Comparison of the effect of Crotalus simus and Crotalus durissus ruruima venoms on the equine antibody response towards Bothrops asper venom: Implications for the production of pol...

by Dos Santos, María Cristina, Arroyo Portilla, Cynthia, Solano Rojas, Sergio, Herrera Vega, María, Villalta Arrieta, Mauren, Segura Ruiz, Álvaro, Estrada Umaña, Ricardo, Gutiérrez, José María, León Montero, Guillermo
Published 2017

Effect of geographical variation of Echis ocellatus, Naja nigricollis and Bitis arietans venoms on their neutralization by homologous and heterologous antivenoms

by Sánchez Brenes, Andrés, Coto Porras, Jorge, Segura Ruiz, Álvaro, Vargas Arroyo, Mariángela, Solano Trejos, María Gabriela, Herrera Vega, María, Villalta Arrieta, Mauren, Estrada Umaña, Ricardo, Gutiérrez, José María
Published 2017

Proteomic and toxinological characterization of the venom of the South African Ringhals cobra Hemachatus haemachatus

by Sánchez Brenes, Andrés, Herrera Vega, María, Villalta Arrieta, Mauren, Solano, Daniela, Segura Ruiz, Álvaro, Lomonte, Bruno, Gutiérrez, José María, León Montero, Guillermo, Vargas Arroyo, Mariángela
Published 2019

Efficacy of IgG and F(ab′)2 Antivenoms to Neutralize Snake Venom-induced Local Tissue Damage as Assessed by the Proteomic Analysis of Wound Exudate

by Rucavado Romero, Alexandra, Escalante Muñoz, Teresa, Shannon, John D., Ayala Castro, Carla N., Villalta Arrieta, Mauren, Gutiérrez, José María, Fox, Jay W.
Published 2017

Antivenomic Assessment of the Immunological Reactivity of EchiTAb-Plus-ICP, an Antivenom for the Treatment of Snakebite Envenoming in Sub-Saharan Africa

by Calvete Chornet, Juan José, Cid, Pedro, Sanz, Libia, Segura Ruiz, Álvaro, Villalta Arrieta, Mauren, Herrera Vega, María, León Montero, Guillermo, Harrison, Robert A., Durfa, Nandul, Nasidi, Abdulsalami, Theakston, R. David G., Warrell, David A., Gutiérrez, José María
Published 2016

Preclinical evaluation of caprylic-acid fractionated IgG antivenom for the treatment of taipan (Oxyuranus scutellatus) envneoming in Papua New Guinea

by Vargas Arroyo, Mariángela, Segura Ruiz, Álvaro, Herrera Vega, María, Villalta Arrieta, Mauren, Estrada Umaña, Ricardo, Cerdas Solís, Maykel, Paiva, Owen K., Matainaho, Teatulohi, Jensen, Simon D., Winkel, Kenneth D., León Montero, Guillermo, Gutiérrez, José María, Williams, David J.
Published 2014

Role of the animal model on the pharmacokinetics of equine-derived antivenoms

by Rojas Araya, Alicia, Vargas Arroyo, Mariángela, Ramírez Arguedas, Nils Antonio, Estrada Umaña, Ricardo, Segura Ruiz, Álvaro, Herrera Vega, María, Villalta Arrieta, Mauren, Gómez Argüello, Aarón, Gutiérrez, José María, León Montero, Guillermo
Published 2017

Comparison of the adjuvant activity of aluminum hydroxide and calcium phosphate on the antibody response towards Bothrops asper snake venom

by Olmedo, Hidekel, Herrera Vega, María, Rojas Sánchez, Leonardo, Villalta Arrieta, Mauren, Vargas Arroyo, Mariángela, Leiguez, Elbio, Teixeira, Catarina de Fátima, Estrada Umaña, Ricardo, Gutiérrez, José María, León Montero, Guillermo, Montero Villalobos, Mavis Lili
Published 2017

Preclinical evaluation of the efficacy of antivenoms for snakebite envenoming: State-of-the-art and challenges ahead

by Solano Trejos, María Gabriela, Pla Ferrer, Davinia, Herrera Vega, María, Segura Ruiz, Álvaro, Vargas Arroyo, Mariángela, Villalta Arrieta, Mauren, Sánchez Brenes, Andrés, Sanz, Libia, Lomonte, Bruno, León Montero, Guillermo, Calvete Chornet, Juan José, Gutiérrez, José María
Published 2018

Development of a chicken-derived antivenom against the taipan snake (Oxyuranus scutellatus) venom and comparison with an equine antivenom

by Navarro Arias, Diego, Vargas Arroyo, Mariángela, Herrera Vega, María, Segura Ruiz, Álvaro, Gómez Argüello, Aarón, Villalta Arrieta, Mauren, Ramírez Arguedas, Nils Antonio, Williams, David J., Gutiérrez, José María, León Montero, Guillermo
Published 2017

Impact of Regional Variation in Bothrops asper Snake Venom on the Design of Antivenoms: Integrating Antivenomics and Neutralization Approaches

by Gutiérrez, José María, Sanz, Libia, Flores Díaz, Marietta, Figueroa, Lucía, Madrigal Villalobos, Marvin, Herrera Vega, María, Villalta Arrieta, Mauren, León Montero, Guillermo, Estrada Umaña, Ricardo, Borges, Adolfo, Alape Girón, Alberto, Calvete Chornet, Juan José
Published 2016