Effect of a killed whole Neospora caninum tachyzoite vaccine on the crude abortion rate of Costa Rican dairy cows under field conditions
A standard field trial was carried out to assess the effect of a commercial Neospora-vaccine based on whole killed tachyzoites (Bovilis–Neoguard, Intervet1) on the abortion rate. Eight hundred and seventy-six cows, over 2.5 months pregnant, belonging to 25 Costa Rican dairy herds, were used in the...
| Autores Principales: | Pérez, E., Frankena, K., ROMERO-ZUÑIGA, JUAN JOSÉ |
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| Formato: | Artículo |
| Idioma: | Inglés |
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Elsevier B.V
2022
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| Acceso en línea: |
http://hdl.handle.net/11056/23266 https://doi.org/10.1016/j.vetpar.2004.06.016 |
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RepoUNACR23266 |
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RepoUNACR232662022-06-13T18:51:07Z Effect of a killed whole Neospora caninum tachyzoite vaccine on the crude abortion rate of Costa Rican dairy cows under field conditions Pérez, E. Frankena, K. ROMERO-ZUÑIGA, JUAN JOSÉ COSTA RICA GANADO DE LECHE DAIRY CATTLE ABORTO EN ANIMALES VACUNA VACCINE ABORTION IN ANIMALS A standard field trial was carried out to assess the effect of a commercial Neospora-vaccine based on whole killed tachyzoites (Bovilis–Neoguard, Intervet1) on the abortion rate. Eight hundred and seventy-six cows, over 2.5 months pregnant, belonging to 25 Costa Rican dairy herds, were used in the analysis. For each cow vaccinated, a cow of the same herd, breed and age category, was selected as control. The period of administration of treatments extended from June to November of 2000. The treatments were administered in two, 5 ml doses 1 month apart, the first dose given between day 75 and 90 of gestation. The incidence of abortion among all treated cows was of 16.0% (140/876). The treatment specific incidence was 11.2% (49/438) and 20.8% (91/438) for the vaccinated and the placebo group, respectively. The prevented fraction by vaccination amounted to 0.46 (95% CI: 0.26, 0.61), and the cumulative incidence ratio for the vaccinated group was 0.54. The Cox hazard ratio was 0.51(95% CI: 0.37, 0.72), meaning that the force of abortion is reduced twice in the vaccinated group. The results of this study, the first one following this type of design, shows that the killed whole Neospora caninum tachyzoite preparation had a reasonable effect on the abortion rate in Costa Rican dairy cattle. # 2004 Elsevier B.V. All rights reserved. Se llevó a cabo un ensayo de campo estándar para evaluar el efecto de una vacuna comercial contra Neospora basada en taquizoítos enteros muertos (Bovilis-Neoguard, Intervet1) sobre la tasa de aborto. En el análisis se utilizaron 876 vacas de más de 2,5 meses de gestación, pertenecientes a 25 rebaños lecheros de Costa Rica. Por cada vaca vacunada, se seleccionó una vaca del mismo rebaño, raza y categoría de edad, como control. El período de administración de los tratamientos se extendió de junio a noviembre de 2000. Los tratamientos se administraron en dos dosis de 5 ml con un mes de diferencia, la primera de ellas entre el día 75 y el 90 de gestación. La incidencia de abortos entre todas las vacas tratadas fue del 16,0% (140/876). La incidencia específica del tratamiento fue del 11,2% (49/438) y del 20,8% (91/438) para el grupo vacunado y el grupo placebo, respectivamente. La fracción prevenida por la vacunación ascendió a 0,46 (IC 95%: 0,26, 0,61), y la razón de incidencia acumulada para el grupo vacunado fue de 0,54. La razón de riesgo de Cox fue de 0,51 (IC 95%: 0,37, 0,72), lo que significa que la fuerza del aborto se reduce dos veces en el grupo vacunado. Los resultados de este estudio, el primero que sigue este tipo de diseño, demuestran que el preparado de taquizoítos muertos de Neospora caninum tuvo un efecto razonable sobre la tasa de aborto en el ganado lechero costarricense. Universidad Nacional, Costa Rica. Escuela de Medicina Veterinaria 2022-06-13T18:48:49Z 2022-06-13T18:48:49Z 2004-06-04 http://purl.org/coar/resource_type/c_6501 http://hdl.handle.net/11056/23266 https://doi.org/10.1016/j.vetpar.2004.06.016 eng Acceso embargado http://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Elsevier B.V Veterinary Parasitology Vol. 123, No. 3–4, 2 : 149-159, 2004. |
| institution |
Universidad Nacional de Costa Rica |
| collection |
Repositorio UNA-Costa Rica |
| language |
Inglés |
| topic |
COSTA RICA GANADO DE LECHE DAIRY CATTLE ABORTO EN ANIMALES VACUNA VACCINE ABORTION IN ANIMALS |
| spellingShingle |
COSTA RICA GANADO DE LECHE DAIRY CATTLE ABORTO EN ANIMALES VACUNA VACCINE ABORTION IN ANIMALS Pérez, E. Frankena, K. ROMERO-ZUÑIGA, JUAN JOSÉ Effect of a killed whole Neospora caninum tachyzoite vaccine on the crude abortion rate of Costa Rican dairy cows under field conditions |
| description |
A standard field trial was carried out to assess the effect of a commercial Neospora-vaccine based on
whole killed tachyzoites (Bovilis–Neoguard, Intervet1) on the abortion rate. Eight hundred and
seventy-six cows, over 2.5 months pregnant, belonging to 25 Costa Rican dairy herds, were used in the
analysis. For each cow vaccinated, a cow of the same herd, breed and age category, was selected as
control. The period of administration of treatments extended from June to November of 2000. The
treatments were administered in two, 5 ml doses 1 month apart, the first dose given between day 75 and
90 of gestation. The incidence of abortion among all treated cows was of 16.0% (140/876). The
treatment specific incidence was 11.2% (49/438) and 20.8% (91/438) for the vaccinated and the placebo
group, respectively. The prevented fraction by vaccination amounted to 0.46 (95% CI: 0.26, 0.61), and
the cumulative incidence ratio for the vaccinated group was 0.54. The Cox hazard ratio was 0.51(95%
CI: 0.37, 0.72), meaning that the force of abortion is reduced twice in the vaccinated group. The results
of this study, the first one following this type of design, shows that the killed whole Neospora caninum
tachyzoite preparation had a reasonable effect on the abortion rate in Costa Rican dairy cattle.
# 2004 Elsevier B.V. All rights reserved. |
| format |
Artículo |
| author |
Pérez, E. Frankena, K. ROMERO-ZUÑIGA, JUAN JOSÉ |
| author_sort |
Pérez, E. |
| title |
Effect of a killed whole Neospora caninum tachyzoite vaccine on the crude abortion rate of Costa Rican dairy cows under field conditions |
| title_short |
Effect of a killed whole Neospora caninum tachyzoite vaccine on the crude abortion rate of Costa Rican dairy cows under field conditions |
| title_full |
Effect of a killed whole Neospora caninum tachyzoite vaccine on the crude abortion rate of Costa Rican dairy cows under field conditions |
| title_fullStr |
Effect of a killed whole Neospora caninum tachyzoite vaccine on the crude abortion rate of Costa Rican dairy cows under field conditions |
| title_full_unstemmed |
Effect of a killed whole Neospora caninum tachyzoite vaccine on the crude abortion rate of Costa Rican dairy cows under field conditions |
| title_sort |
effect of a killed whole neospora caninum tachyzoite vaccine on the crude abortion rate of costa rican dairy cows under field conditions |
| publisher |
Elsevier B.V |
| publishDate |
2022 |
| url |
http://hdl.handle.net/11056/23266 https://doi.org/10.1016/j.vetpar.2004.06.016 |
| _version_ |
1796097382260146176 |
| score |
12.041432 |