An in vivo model to study the anti-malaric capacity of plant extracts
An in vivo model to study the antimalaric effect of plant extracts is described. White mice (25-30g body weight) are treated subcutaneously with 0.6ml of the diluted extract starting seven days before P. berghei infection; treatment continues until death or for 30 days. Simultaneously 0.2ml of the e...
| Autores Principales: | Chinchilla, Misael, Guerrero., OIga, Abarca, Gabriela, Barrios, , Mariano, Castro, Oscar |
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| Formato: | Artículo |
| Idioma: | Inglés |
| Publicado: |
Universidad de Costa Rica
2022
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| Materias: | |
| Acceso en línea: |
http://hdl.handle.net/11056/22769 |
| Sumario: |
An in vivo model to study the antimalaric effect of plant extracts is described. White mice (25-30g body weight) are treated subcutaneously with 0.6ml of the diluted extract starting seven days before P. berghei infection; treatment continues until death or for 30 days. Simultaneously 0.2ml of the extract are applied per os starting three days before infection. In a test of the model, treated and non-treated animals differed in body weight, survival time, haematocrite, parasitemia development, and spleen or liver weight of recent dead or killed mice. |
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