Temporal trends in antimicrobial resistance of fecal Escherichia coli from deer
The changing epidemiologic role of wildlife as reservoirs of antimicrobial-resistant bacteria (ARB) is poorly understood. In this study, we characterize the phenotypic resistance of commensal Escherichia coli from fecal samples of 879 individual white-tailed (Odocoileus virginianus; WTD) over a te...
| Autores Principales: | Ballash, Gregory A., MUNOZ VARGAS, LOHENDY, Albers, Amy, Dennis, Patricia, LeJeune, Jeffrey T., Mollenkopf, Dixie, Wittum, Thomas |
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| Formato: | Artículo |
| Idioma: | Inglés |
| Publicado: |
EcoHealth Alliance
2021
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| Materias: | |
| Acceso en línea: |
http://hdl.handle.net/11056/21583 https://doi.org/10.1007/s10393-021-01559-3 |
| Sumario: |
The changing epidemiologic role of wildlife as reservoirs of antimicrobial-resistant bacteria (ARB) is
poorly understood. In this study, we characterize the phenotypic resistance of commensal Escherichia coli from
fecal samples of 879 individual white-tailed (Odocoileus virginianus; WTD) over a ten-year period and analyze
resistance patterns. Our results show commensal E. coli from WTD had significant linear increases in reduced
susceptibility to 5 of 12 antimicrobials, including broad-spectrum cephalosporins and fluoroquinolones, from
2006 to 2016. In addition, the relative frequency distribution of minimal inhibitory concentrations of two
additional antimicrobials shifted towards higher values from across the study period. The prevalence of
multidrug-resistant commensal E. coli increased over the study period with a prevalence of 0%, 2.2%, and 3.7%
in 2006, 2012, and 2016, respectively. WTD may be persistently and increasingly exposed to antibiotics or their
residues, ARB, and/or antimicrobial resistance genes via contaminated environments like surface water
receiving treated wastewater effluent. |
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