Third-dimensional organ and tissue printing: techniques, applications, and limitations
Third-dimensional (3D) printing is the additive manufacturing process of a three-dimensional object, controlled by a computer program. Its three major stages are preprocessing, processing and postprocessing. In addition, with regard to processing, the different techniques for obtaining it include la...
Autores Principales: | Yang-Lee, Iria, Salas-Sánchez, Francisco, Pomares-Wauters, Geget, Ramos-Gamboa, María Fernanda, Godfrey-Lowis, Melody, Mora-Román, Juan José |
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Editorial Tecnológica de Costa Rica (entidad editora)
2018
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https://revistas.tec.ac.cr/index.php/tec_marcha/article/view/3900 https://hdl.handle.net/2238/11811 |
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RepoTEC118112020-09-25T23:12:03Z Third-dimensional organ and tissue printing: techniques, applications, and limitations Bioimpresión de órganos y tejidos en tercera dimensión: técnicas, aplicaciones y limitaciones Yang-Lee, Iria Salas-Sánchez, Francisco Pomares-Wauters, Geget Ramos-Gamboa, María Fernanda Godfrey-Lowis, Melody Mora-Román, Juan José Bioimpresión andamio biotinta bioética Bioprinting scaffold bioink bioethics. Third-dimensional (3D) printing is the additive manufacturing process of a three-dimensional object, controlled by a computer program. Its three major stages are preprocessing, processing and postprocessing. In addition, with regard to processing, the different techniques for obtaining it include laser-assisted bioprinting, thermal printing using cartridges and bioink, direct-write bioprinting, and bioprinting using spheroids. Some of the general applications of the mentioned methods are hepatic and cardiac tissue manufacture, and myocytes differentiation, which are useful for advance in medicine and in the development of drugs. Even so, there are challenges to overcome and limitations related to them, including the adequate development of organs and tissues vasculature, and the fact of transplanting an organ obtained by bioprinting to a patient; besides, postsurgery care, considered as part of the immunovigilance. As a complement, a series of bioethical implications should be undertaken; among them, the implementation of informed consent is relevant in every step of the therapy to which the patient submits. This implies the creation of laws and guides to regulate the process. La impresión en tercera dimensión (3D) es el proceso de manufactura controlado por un programa informático de un objeto tridimensional con materiales que se disponen por capas. Sus tres grandes etapas son preprocesamiento, procesamiento y postprocesamiento. En lo que respecta al procesamiento, las distintas técnicas aplicadas abarcan la bioimpresión asistida por láser, la impresión térmica por medio de cartuchos y biotinta, la bioimpresión de escritura directa y la bioimpresión por medio de esferoides. Algunas de las aplicaciones generales de los métodos mencionados son la fabricación de tejido hepático y cardíaco, y la diferenciación de miocitos, ambas útiles para el avance en medicina y en el desarrollo de fármacos. Aun así, existen retos y limitaciones en relación con estos, entre los cuales destacan el desarrollo adecuado de la vasculatura de los órganos y tejidos creados, y el logro del trasplante al paciente de un órgano obtenido por bioimpresión, además de los cuidados de postcirugía, como parte de la inmunovigilancia. Como complemento, se deben considerar una serie de implicaciones bioéticas, de las cuales la implementación del consentimiento informado es relevante en todo paso de la terapia a la que se someta el paciente. Esto implicala creación de leyes y guías que permitan regular el proceso. 2018-07-11 2020-09-25T23:12:03Z 2020-09-25T23:12:03Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://revistas.tec.ac.cr/index.php/tec_marcha/article/view/3900 10.18845/tm.v31i3.3900 https://hdl.handle.net/2238/11811 spa https://revistas.tec.ac.cr/index.php/tec_marcha/article/view/3900/pdf application/pdf Editorial Tecnológica de Costa Rica (entidad editora) Tecnología en marcha Journal; Vol. 31, Núm. 3: Julio-Setiembre 2018; pág. 41-51 Revista Tecnología en Marcha; Vol. 31, Núm. 3: Julio-Setiembre 2018; pág. 41-51 2215-3241 0379-3982 |
institution |
Tecnológico de Costa Rica |
collection |
Repositorio TEC |
language |
Español |
topic |
Bioimpresión andamio biotinta bioética Bioprinting scaffold bioink bioethics. |
spellingShingle |
Bioimpresión andamio biotinta bioética Bioprinting scaffold bioink bioethics. Yang-Lee, Iria Salas-Sánchez, Francisco Pomares-Wauters, Geget Ramos-Gamboa, María Fernanda Godfrey-Lowis, Melody Mora-Román, Juan José Third-dimensional organ and tissue printing: techniques, applications, and limitations |
description |
Third-dimensional (3D) printing is the additive manufacturing process of a three-dimensional object, controlled by a computer program. Its three major stages are preprocessing, processing and postprocessing. In addition, with regard to processing, the different techniques for obtaining it include laser-assisted bioprinting, thermal printing using cartridges and bioink, direct-write bioprinting, and bioprinting using spheroids. Some of the general applications of the mentioned methods are hepatic and cardiac tissue manufacture, and myocytes differentiation, which are useful for advance in medicine and in the development of drugs. Even so, there are challenges to overcome and limitations related to them, including the adequate development of organs and tissues vasculature, and the fact of transplanting an organ obtained by bioprinting to a patient; besides, postsurgery care, considered as part of the immunovigilance. As a complement, a series of bioethical implications should be undertaken; among them, the implementation of informed consent is relevant in every step of the therapy to which the patient submits. This implies the creation of laws and guides to regulate the process. |
format |
Artículo |
author |
Yang-Lee, Iria Salas-Sánchez, Francisco Pomares-Wauters, Geget Ramos-Gamboa, María Fernanda Godfrey-Lowis, Melody Mora-Román, Juan José |
author_sort |
Yang-Lee, Iria |
title |
Third-dimensional organ and tissue printing: techniques, applications, and limitations |
title_short |
Third-dimensional organ and tissue printing: techniques, applications, and limitations |
title_full |
Third-dimensional organ and tissue printing: techniques, applications, and limitations |
title_fullStr |
Third-dimensional organ and tissue printing: techniques, applications, and limitations |
title_full_unstemmed |
Third-dimensional organ and tissue printing: techniques, applications, and limitations |
title_sort |
third-dimensional organ and tissue printing: techniques, applications, and limitations |
publisher |
Editorial Tecnológica de Costa Rica (entidad editora) |
publishDate |
2018 |
url |
https://revistas.tec.ac.cr/index.php/tec_marcha/article/view/3900 https://hdl.handle.net/2238/11811 |
_version_ |
1796140568812716032 |
score |
12.040382 |