Proteomics of Wound Exudate in Snake Venom-Induced Pathology: Search for Biomarkers To Assess Tissue Damage and Therapeutic Success

por Rucavado Romero, Alexandra, Escalante Muñoz, Teresa, Shannon, John D., Gutiérrez, José María, Fox, Jay W.
Publicado 2016

Skin Pathology Induced by Snake Venom Metalloproteinase: Acute Damage, Revascularization, and Re-epithelization in a Mouse Ear Model

por Jiménez Álvarez, Natalia, Escalante Muñoz, Teresa, Gutiérrez, José María, Rucavado Romero, Alexandra
Publicado 2016

Effectiveness of batimastat, a synthetic inhibitor of matrix metalloproteinases, in neutralizing local tissue damage induced by BaP1, a hemorrhagic metalloproteinase from the venom...

por Escalante Muñoz, Teresa, Franceschi, Aida, Rucavado Romero, Alexandra, Gutiérrez, José María
Publicado 2017

Systemic effects induced by the venom of the snake Bothrops caribbaeus in a murine model

por Herrera Arias, Cristina, Rucavado Romero, Alexandra, Warrell, David A., Gutiérrez, José María
Publicado 2017

Poor regenerative outcome after skeletal muscle necrosis induced by Bothrops asper venom: alterations in microvasculature and nerves

por Hernández, Rosario, Cabalceta, Carmen, Saravia Otten, Patricia, Chaves, Alessandra, Gutiérrez, José María, Rucavado Romero, Alexandra
Publicado 2014

Bothrops asper metalloproteinase BaP1 is inhibited by alpha(2)-macroglobulin and mouse serum and does not induce systemic hemorrhage or coagulopathy

por Escalante Muñoz, Teresa, Rucavado Romero, Alexandra, Kamiguti, Aura S., Theakston, R. David G., Gutiérrez, José María
Publicado 2017

Hemorrhage Caused by Snake Venom Metalloproteinases: A Journey of Discovery and Understanding

por Gutiérrez, José María, Escalante Muñoz, Teresa, Rucavado Romero, Alexandra, Herrera Arias, Cristina
Publicado 2017

Hemorrhage induced by snake venom metalloproteinases: biochemical and biophysical mechanisms involved in microvessel damage

por Gutiérrez, José María, Rucavado Romero, Alexandra, Escalante Muñoz, Teresa, Díaz Oreiro, Cecilia
Publicado 2017

Key events in microvascular damage induced by snake venom hemorrhagic metalloproteinases

por Escalante Muñoz, Teresa, Rucavado Romero, Alexandra, Fox, Jay W., Gutiérrez, José María
Publicado 2017

Characterization of events associated with apoptosis/anoikis induced by snake venom metalloproteinase BaP1 on human endothelial cells

por Díaz Oreiro, Cecilia, Valverde, Lorena, Brenes García, Oscar Gerardo, Rucavado Romero, Alexandra, Gutiérrez, José María
Publicado 2017

Pulmonary hemorrhage induced by jararhagin, a metalloproteinase from Bothrops jararaca snake venom

por Escalante Muñoz, Teresa, Núñez, Javier, Moura Da Silva, Ana M., Rucavado Romero, Alexandra, Theakston, R. David G., Gutiérrez, José María
Publicado 2017

Thrombocytopenia and platelet hypoaggregation induced by Bothrops asper snake venom. Toxins involved and their contribution to metalloproteinase-induced pulmonary hemorrhage.

por Rucavado Romero, Alexandra, Soto Morera, Mónica, Escalante Muñoz, Teresa, Loría Masís, Gilbert David, Arni, Raghuvir K., Gutiérrez, José María
Publicado 2016

Inflammatory effects of BaP1 a metalloproteinase isolated from Bothrops asper snake venom: leukocyte recruitment and release of cytokines

por Fernandes, Cristina Maria, Zamunér, Stella Regina, Zuliani, Juliana Pavan, Rucavado Romero, Alexandra, Gutiérrez, José María, Teixeira, Catarina de Fátima
Publicado 2016

Role of collagens and perlecan in microvascular stability: exploring the mechanism of capillary vessel damage by snake venom metalloproteinases

por Escalante Muñoz, Teresa, Ortiz Chaves, Natalia, Rucavado Romero, Alexandra, Sánchez, Eladio, Richardson, Michael, Fox, Jay W., Gutiérrez, José María
Publicado 2014

The lethality test used for estimating the potency of antivenoms against Bothrops asper snake venom: Pathophysiological mechanisms, prophylactic analgesia, and a surrogate in vitro...

por Chacón Valverde, Francisco, Oviedo Cerdas, Andrea, Escalante Muñoz, Teresa, Solano Trejos, María Gabriela, Rucavado Romero, Alexandra, Gutiérrez, José María
Publicado 2017

Increments in cytokines and matrix metalloproteinases in skeletal muscle after injection of tissue-damaging toxins from the venom of the snake Bothrops asper

por Rucavado Romero, Alexandra, Escalante Muñoz, Teresa, Teixeira, Catarina de Fátima, Fernandes, Cristina Maria, Díaz Oreiro, Cecilia, Gutiérrez, José María
Publicado 2017

Neutralization of local tissue damage induced by Bothrops asper (terciopelo) snake venom

por Gutiérrez, José María, León Montero, Guillermo, Rojas Céspedes, Gustavo, Lomonte, Bruno, Rucavado Romero, Alexandra, Chaves Mora, Fernando
Publicado 2017

Tissue pathology induced by snake venoms: How to understand a complex pattern of alterations from a systems biology perspective?

por Gutiérrez, José María, Rucavado Romero, Alexandra, Escalante Muñoz, Teresa, Lomonte, Bruno, Angulo Ugalde, Yamileth, Fox, Jay W.
Publicado 2016

Unresolved issues in the understanding of the pathogenesis of local tissue damage induced by snake venoms

por Gutiérrez, José María, Rucavado Romero, Alexandra, Escalante Muñoz, Teresa, Herrera Arias, Cristina, Fernández Ulate, Julián, Lomonte, Bruno, Fox, Jay W.
Publicado 2019

Modulation of the Susceptibility of Human Erythrocytes to Snake Venom Myotoxic Phospholipases A2: Role of Negatively Charged Phospholipids as Potential Membrane Binding Sites

por Díaz Oreiro, Cecilia, León Montero, Guillermo, Rucavado Romero, Alexandra, Rojas Campos, Norman, Schroit, Alan J., Gutiérrez, José María
Publicado 2017