Neutralizing properties of Varespladib toward group I and II myotoxic phospholipases A2

por Bryan Quirós, Wendy, Fernández Ulate, Julián, Gutiérrez, José María, Lewin, Matthew R., Lomonte, Bruno
Publicado 2020

Varespladib (LY315920) and methyl Varespladib (LY333013) abrogate or delay lethality induced by presynaptically-acting neurotoxic snake venoms

por Gutiérrez, José María, Lewin, Matthew R., Williams, David J., Lomonte, Bruno
Publicado 2021

The synthetic Varespladib molecule is a multi-functional inhibitor for PLA2 and PLA2-like ophidic toxins

por Salvador, Guilherme Henrique Marchi, Borges, Rafael J., Lomonte, Bruno, Lewin, Matthew R., Fontes, Marcos Roberto de Mattos
Publicado 2021

Structural basis for phospholipase A2-like toxin inhibition by the synthetic compound Varespladib (LY315920)

por Salvador, Guilherme Henrique Marchi, Gomes, Antoniel A. S., Bryan Quirós, Wendy, Fernández Ulate, Julián, Lewin, Matthew R., Gutiérrez, José María, Lomonte, Bruno, Fontes, Marcos Roberto de Mattos
Publicado 2020

Structural basis of the myotoxic inhibition of the Bothrops pirajai PrTX-I by the synthetic varespladib

por Salvador, Guilherme H. M., Pinto, Êmylle K. R., Ortolani, Paula L., Forte Dias, Consuelo L., Cavalcante, Walter L. G., Soares, Adreimar M., Lomonte, Bruno, Lewin, Matthew R., Fontes, Marcos Roberto de Mattos
Publicado 2023