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Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities

by Quesada Gómez, Carlos, López Ureña, Diana, Chumbler, Nicole, Kroh, Heather K., Castro Peña, Carolina, Rodríguez Sánchez, César, Orozco Aguilar, Josué, González Camacho, Sara María, Rucavado Romero, Alexandra, Guzmán Verri, Caterina, Lawley, Trevor D., Lacy, D. Borden, Chaves Olarte, Esteban
Published 2017

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Bothrops asper metalloproteinase BaP1 is inhibited by alpha(2)-macroglobulin and mouse serum and does not induce systemic hemorrhage or coagulopathy

by Escalante Muñoz, Teresa, Rucavado Romero, Alexandra, Kamiguti, Aura S., Theakston, R. David G., Gutiérrez, José María
Published 2017

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Assessment of metalloproteinase inhibitors clodronate and doxycycline in the neutralization of hemorrhage and coagulopathy induced by Bothrops asper snake venom

by Rucavado Romero, Alexandra, Henríquez, Mónica, García, Jonielle, Gutiérrez, José María
Published 2016

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Increments in cytokines and matrix metalloproteinases in skeletal muscle after injection of tissue-damaging toxins from the venom of the snake Bothrops asper

by Rucavado Romero, Alexandra, Escalante Muñoz, Teresa, Teixeira, Catarina de Fátima, Fernandes, Cristina Maria, Díaz Oreiro, Cecilia, Gutiérrez, José María
Published 2017

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Inhibition of local hemorrhage and dermonecrosis induced by Bothrops asper snake venom: effectiveness of early in situ administration of the peptidomimetic metalloproteinase inhibi...

by Rucavado Romero, Alexandra, Escalante Muñoz, Teresa, Franceschi, Aida, Chaves Mora, Fernando, León Montero, Guillermo, Cury, Yara, Ovadia, Michael, Gutiérrez, José María
Published 2017

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Skeletal muscle necrosis and regeneration after injection of Thalassophryne nattereri (niquim) fish venom in mice

by Lopes Ferreira, Mónica, Núñez, Javier, Rucavado Romero, Alexandra, Farsky, Sandra H. P., Lomonte, Bruno, Angulo Ugalde, Yamileth, Moura Da Silva, Ana M., Gutiérrez, José María
Published 2017

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Isolation and characterization of a serine proteinase with thrombin-like activity from the venom of the snake Bothrops asper

by Pérez, Aida Verónica, Rucavado Romero, Alexandra, Sanz, Libia, Calvete Chornet, Juan José, Gutiérrez, José María
Published 2016

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Identification of residues critical for toxicity in Clostridium perfringens phospholipase C, the key toxin in gas gangrene

by Alape Girón, Alberto, Flores Díaz, Marietta, Guillouard, Isabelle, Naylor, Claire E., Titball, Richard, Rucavado Romero, Alexandra, Lomonte, Bruno, Basak, Ajit K., Gutiérrez, José María, Cole, Steward T., Thelestam, Mónica
Published 2017

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The lethality test used for estimating the potency of antivenoms against Bothrops asper snake venom: Pathophysiological mechanisms, prophylactic analgesia, and a surrogate in vitro...

by Chacón Valverde, Francisco, Oviedo Cerdas, Andrea, Escalante Muñoz, Teresa, Solano Trejos, María Gabriela, Rucavado Romero, Alexandra, Gutiérrez, José María
Published 2017

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Experimental pathophysiology of systemic alterations induced by Bothrops asper snake venom

by Gutiérrez, José María, Escalante Muñoz, Teresa, Rucavado Romero, Alexandra
Published 2016

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Systemic effects induced by the venom of the snake Bothrops caribbaeus in a murine model

by Herrera Arias, Cristina, Rucavado Romero, Alexandra, Warrell, David A., Gutiérrez, José María
Published 2017

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Skin Pathology Induced by Snake Venom Metalloproteinase: Acute Damage, Revascularization, and Re-epithelization in a Mouse Ear Model

by Jiménez Álvarez, Natalia, Escalante Muñoz, Teresa, Gutiérrez, José María, Rucavado Romero, Alexandra
Published 2016

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Effectiveness of batimastat, a synthetic inhibitor of matrix metalloproteinases, in neutralizing local tissue damage induced by BaP1, a hemorrhagic metalloproteinase from the venom...

by Escalante Muñoz, Teresa, Franceschi, Aida, Rucavado Romero, Alexandra, Gutiérrez, José María
Published 2017

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Bothrops asper snake venom and its metalloproteinase BaP–1 activate the complement system. Role in leucocyte recruitment

by Farsky, Sandra H. P., Gonçalves, Luís Roberto de Camargo, Gutiérrez, José María, Correa, Adriana P., Rucavado Romero, Alexandra, Gasque, Philippe, Tambourgi, Denise V.
Published 2017

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Poor regenerative outcome after skeletal muscle necrosis induced by Bothrops asper venom: alterations in microvasculature and nerves

by Hernández, Rosario, Cabalceta, Carmen, Saravia Otten, Patricia, Chaves, Alessandra, Gutiérrez, José María, Rucavado Romero, Alexandra
Published 2014

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Proteomics of Wound Exudate in Snake Venom-Induced Pathology: Search for Biomarkers To Assess Tissue Damage and Therapeutic Success

by Rucavado Romero, Alexandra, Escalante Muñoz, Teresa, Shannon, John D., Gutiérrez, José María, Fox, Jay W.
Published 2016

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Muscle Tissue Damage Induced by the Venom of Bothrops asper: Identification of Early and Late Pathological Events through Proteomic Analysis

by Herrera Arias, Cristina, Macêdo, Jéssica Kele A., Feoli Grant, Andrés, Escalante Muñoz, Teresa, Rucavado Romero, Alexandra, Gutiérrez, José María, Fox, Jay W.
Published 2017

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Snake Venomics of the Lesser Antillean Pit Vipers Bothrops caribbaeus and Bothrops lanceolatus: Correlation with Toxicological Activities and Immunoreactivity of a Heterologous Ant...

by Gutiérrez, José María, Sanz, Libia, Escolano, José, Fernández Ulate, Julián, Lomonte, Bruno, Angulo Ugalde, Yamileth, Rucavado Romero, Alexandra, Warrell, David A., Calvete Chornet, Juan José
Published 2016

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Hemorrhage induced by snake venom metalloproteinases: biochemical and biophysical mechanisms involved in microvessel damage

by Gutiérrez, José María, Rucavado Romero, Alexandra, Escalante Muñoz, Teresa, Díaz Oreiro, Cecilia
Published 2017

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Efficacy of IgG and F(ab′)2 Antivenoms to Neutralize Snake Venom-induced Local Tissue Damage as Assessed by the Proteomic Analysis of Wound Exudate

by Rucavado Romero, Alexandra, Escalante Muñoz, Teresa, Shannon, John D., Ayala Castro, Carla N., Villalta Arrieta, Mauren, Gutiérrez, José María, Fox, Jay W.
Published 2017

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