Reduced activity of Arabidopsis chromosome-cohesion regulator gene CTF7/ECO1 alters cytosine methylation status and retrotransposon expression

ORCID IDs: 0000-0003-1729-0561 (P.B.-V.); 0000-0003-3459-1331 (G.-Y.J.)

Main Authors: Bolaños Villegas, Pablo Alberto, Jauh, Guang-Yuh
Format: Artículo
Language: Inglés
Published: 2016
Subjects:
Online Access: http://www.tandfonline.com/doi/full/10.1080/15592324.2015.1013794
http://hdl.handle.net/10669/28117
id RepoKERWA28117
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spelling RepoKERWA281172018-06-13T15:58:27Z Reduced activity of Arabidopsis chromosome-cohesion regulator gene CTF7/ECO1 alters cytosine methylation status and retrotransposon expression Bolaños Villegas, Pablo Alberto Jauh, Guang-Yuh Arabidopsis thaliana Metilación de ADN CTF7/ECO1 ORCID IDs: 0000-0003-1729-0561 (P.B.-V.); 0000-0003-3459-1331 (G.-Y.J.) Multicellular organisms such as higher plants require timely regulation of DNA replication and cell division to grow and develop. Recent work in Arabidopsis has shown that chromosome segregation during meiosis and mitosis depends on the activity of several genes that in yeast are involved in the establishment of chromosomal cohesion. In this process, proteins of the STRUCTURAL MAINTENANCE OF CHROMOSOMES (SMC) family tether chromosomes and establish inter- and intrachromosomal connections. In Arabidopsis, recruitment of SMC proteins and establishment of cohesion during key stages of the cell cycle depend on the activity of CHROMOSOME TRANSMISSION FIDELITY 7/ ESTABLISHMENT OF COHESION 1 (CTF7/ECO1). Here we show that loss of CTF7/ECO1 activity alters the status of cytosine methylation in both intergenic regions and transposon loci. An increase in expression was also observed for transposon copia28, which suggests a link between CTF7/ECO1 activity, DNA methylation and gene silencing. More work is needed to determine the mechanistic relationships that intervene in this process. Academia Sinica (Taiwan) National Science and Technology Program for Agricultural Biotechnology (NSTP/AB, 098S0030055-AA, Taiwan) Ministry of Science and Technology (99-2321- B-001-036-MY3 and 102-2321-B-001-040-MY3) Universidad de Costa Rica UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Agroalimentarias::Estación Experimental Agrícola Fabio Baudrit Moreno (EEAFBM) 2016-06-23T20:18:39Z 2016-06-23T20:18:39Z 2015-05-01 info:eu-repo/semantics/article Artículo científico http://www.tandfonline.com/doi/full/10.1080/15592324.2015.1013794 1559-2316 ESSN: 1559-2324 http://hdl.handle.net/10669/28117 doi.org/10.1080/15592324.2015.1013794 en_US application/pdf Plant Signaling & Behavior 10:5, e1013794; May 2015
institution Universidad de Costa Rica
collection Repositorio KERWA
language Inglés
topic Arabidopsis thaliana
Metilación de ADN
CTF7/ECO1
spellingShingle Arabidopsis thaliana
Metilación de ADN
CTF7/ECO1
Bolaños Villegas, Pablo Alberto
Jauh, Guang-Yuh
Reduced activity of Arabidopsis chromosome-cohesion regulator gene CTF7/ECO1 alters cytosine methylation status and retrotransposon expression
description ORCID IDs: 0000-0003-1729-0561 (P.B.-V.); 0000-0003-3459-1331 (G.-Y.J.)
format Artículo
author Bolaños Villegas, Pablo Alberto
Jauh, Guang-Yuh
author_sort Bolaños Villegas, Pablo Alberto
title Reduced activity of Arabidopsis chromosome-cohesion regulator gene CTF7/ECO1 alters cytosine methylation status and retrotransposon expression
title_short Reduced activity of Arabidopsis chromosome-cohesion regulator gene CTF7/ECO1 alters cytosine methylation status and retrotransposon expression
title_full Reduced activity of Arabidopsis chromosome-cohesion regulator gene CTF7/ECO1 alters cytosine methylation status and retrotransposon expression
title_fullStr Reduced activity of Arabidopsis chromosome-cohesion regulator gene CTF7/ECO1 alters cytosine methylation status and retrotransposon expression
title_full_unstemmed Reduced activity of Arabidopsis chromosome-cohesion regulator gene CTF7/ECO1 alters cytosine methylation status and retrotransposon expression
title_sort reduced activity of arabidopsis chromosome-cohesion regulator gene ctf7/eco1 alters cytosine methylation status and retrotransposon expression
publishDate 2016
url http://www.tandfonline.com/doi/full/10.1080/15592324.2015.1013794
http://hdl.handle.net/10669/28117
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