Ultraestructura de las células adenohipofisiarias de la rata blanca sometida al efecto de una benzodiazepina en forma crónica*

Abstract: The ultrastructure of the pars anterior (adenohypophysis), treated with diazepam (2.5 mg/Kg) has been studied by thin sections and electron microscopy. The structure of Tirotrophs, Corticotrophs, Gonadotrophs, and Mamotrophs cells were described. Ultrastructural modifications were not obse...

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Main Authors: Sancho Ugalde, Hilda, Ureña Calderón, Francisco
Format: Artículo
Language: Español
Published: Universidad de Costa Rica 2016
Online Access: http://revistas.ucr.ac.cr/index.php/rbt/article/view/24104
http://hdl.handle.net/10669/26375
Summary: Abstract: The ultrastructure of the pars anterior (adenohypophysis), treated with diazepam (2.5 mg/Kg) has been studied by thin sections and electron microscopy. The structure of Tirotrophs, Corticotrophs, Gonadotrophs, and Mamotrophs cells were described. Ultrastructural modifications were not observed. It is concluded that the cronic treatment with diazepam did not produce any visible ultrastructural effects in the secretory cells of the adenohypophysis; maybe because the diazepam has a short life time and due to the small effect of the diazepam metabolites in this species.