Severidad de la enfermedad periodontal en una familia costarricense -Posible ligamen hereditario-

The purpose of this study was to determine the expression of periodontal disease within an extended costarican family. A periodontal assessment was conducted by measuring pocket probing depths on 6 sites of all standing teeth, using a UNC-15 probe (Hu-Friedy, Chicago, USA). General medical and denta...

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Autores Principales: Murillo Knudsen, Gina, Silva de la Fuente, Sandra, Kowolik, Michael, Cervantes Chavarría, Andrés, Mora Solano, Gerardo, Barba Ramírez, Pilar
Formato: Artículo
Idioma: Español
Publicado: Universidad de Costa Rica 2011
Acceso en línea: http://revistas.ucr.ac.cr/index.php/Odontos/article/view/4781
http://hdl.handle.net/10669/21382
Sumario: The purpose of this study was to determine the expression of periodontal disease within an extended costarican family. A periodontal assessment was conducted by measuring pocket probing depths on 6 sites of all standing teeth, using a UNC-15 probe (Hu-Friedy, Chicago, USA). General medical and dental histories were also obtained and peripheral venous blood collected in order to determine serum cytokine levels and genetic polymorphisms. Ethical committee approval was obtained and all participants gave written informed consent. All members of the family presented some degree of periodontal disease and those with more severe disease had alterations in IL-1α and the same IL-6 polymorphism. It is hypothesized that this may be related to the inflammatory status and levels of alveolar bone loss.