Animal models of fear and anxiety: neurobehavioral descriptions

Animal models of fear and anxiety have been widely used for the comprehension of anxiety disorders in humans,?however, it has not been easy to distinguish between both concepts at physiological and behavioral levels. One way to model?anxiety disorders is through behavioral tests of anxiety, (such as...

Full description

Main Authors: Mora Gallegos, Andrea, Salas Castillo, Sof?a
Format: Artículo
Language: Español
Published: 2015
Subjects:
Online Access: http://revistas.ucr.ac.cr/index.php/actualidades/article/view/14595
http://hdl.handle.net/10669/12719
Summary: Animal models of fear and anxiety have been widely used for the comprehension of anxiety disorders in humans,?however, it has not been easy to distinguish between both concepts at physiological and behavioral levels. One way to model?anxiety disorders is through behavioral tests of anxiety, (such as the elevated plus maze and the open field test), and fear (using?the fear conditioning paradigm and active avoidance). Furthermore, animal models are relevant to study the involvement of?different brain areas, like the amygdala, hippocampus and prefrontal cortex. In general, fear and anxiety can be considered as?normal adaptive responses; however, elevated levels of both might generate detrimental consequences for the individual.