WALDENSTR?M MACROGLOBULINEMIA; CASE REPORT AND UPDATE

The Waldenstr?m Macroglobulinemia?is a rare hematologic malignancy characterized by?medullar infiltration of ?lymphocytes clonally related, which secrete monoclonal IgM protein. According to the?World Health Organization ?classification, this entity corresponds to a B-cell No Hodgkin Linfom known as...

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Main Authors: Quir?s Quir?s, William, Rojas Castrillo, Yaoska
Format: Artículo
Language: Español
Published: 2015
Subjects:
Online Access: http://revistas.ucr.ac.cr/index.php/medica/article/view/8071
http://hdl.handle.net/10669/12428
Summary: The Waldenstr?m Macroglobulinemia?is a rare hematologic malignancy characterized by?medullar infiltration of ?lymphocytes clonally related, which secrete monoclonal IgM protein. According to the?World Health Organization ?classification, this entity corresponds to a B-cell No Hodgkin Linfom known as lymphoplasmacytic lymphoma that occurs most often in people over 65 years and particularly in Caucasian males. It is essential to make a proper differential diagnosis between this disease and other similar entities associated with monoclonal component. The etiology is unknown but has been associated with genetic?factors and family. We report a case of a patient with symptomatic?Waldenstr?m Macroglobulinemia, which?present an aggressive clinical picture of retinal ?bleeding ?plus others typical?signs caused by the disease.