Gene admixture in the Costa Rican population

art?culo cient?fico -- Universidad de Costa Rica, Instituto de Investigaciones en Salud. 2003. Este documento es privado debido a limitaciones de derechos de autor.

Main Authors: Morera Brenes, Bernal, Barrantes Mes?n, Ramiro, Mar?n Rojas, Rafael
Format: Artículo
Language: Inglés
Published: Ann Hum Genet; 67 (1) p. 71-80 2015
Subjects:
Online Access: http://onlinelibrary.wiley.com/doi/10.1046/j.1469-1809.2003.00010.x/epdf
http://hdl.handle.net/10669/11386
id RepoKERWA11386
recordtype dspace
spelling RepoKERWA113862018-06-20T16:42:55Z Gene admixture in the Costa Rican population Morera Brenes, Bernal Barrantes Mes?n, Ramiro Mar?n Rojas, Rafael Gen?tica Diversidad genetica Estudios ?tnicos art?culo cient?fico -- Universidad de Costa Rica, Instituto de Investigaciones en Salud. 2003. Este documento es privado debido a limitaciones de derechos de autor. The general population of Costa Rica has sometimes been considered to be the product of an amalgamation of groups of diverse origin. To determine the magnitude of accumulated admixture since Spanish colonization, 11 classic genetic markers were analyzed in a total of 2196 individuals originating from five distinct regions of the country. A maximum likelihood approach was used. The proportions of genes of European, Amerindian and African ancestry were found to be 61%, 30% and 9% of the total population, respectively. Variation was observed at a regional level, with an increased European influence in the North (66%) and Central (65%) regions. Meanwhile an increase in Amerindian ancestry was found in the South (38%), and a higher incidence in the contribution of African genes was detected in the coastal regions (13% in the Atlantic and 14% in the North Pacific). A principal component (PC) analysis showed that 76% of the existing variability can be explained by the first two PCs, which is in agreement with the variations observed in the admixture process by geographic area. It has been concluded that the Costa Rican population is truly trihybrid, similar to populations in other Latin American countries; however, it differs from them fundamentally by the proportion of gene flow from ancestral populations. Universidad de Costa Rica. Instituto de Investigaciones en Salud UCR::Vicerrector?a de Investigaci?n::Unidades de Investigaci?n::Ciencias de la Salud::Instituto de Investigaciones en Salud (INISA) 2015-04-16T15:54:14Z 2015-04-16T15:54:14Z 2003 info:eu-repo/semantics/article Art?culo cient?fico http://onlinelibrary.wiley.com/doi/10.1046/j.1469-1809.2003.00010.x/epdf 0003-4800 http://hdl.handle.net/10669/11386 en_US application/pdf Ann Hum Genet; 67 (1) p. 71-80 Annals of Human Genetics 67:71?80. 2003
institution Universidad de Costa Rica
collection Repositorio KERWA
language Inglés
topic Gen?tica
Diversidad genetica
Estudios ?tnicos
spellingShingle Gen?tica
Diversidad genetica
Estudios ?tnicos
Morera Brenes, Bernal
Barrantes Mes?n, Ramiro
Mar?n Rojas, Rafael
Gene admixture in the Costa Rican population
description art?culo cient?fico -- Universidad de Costa Rica, Instituto de Investigaciones en Salud. 2003. Este documento es privado debido a limitaciones de derechos de autor.
format Artículo
author Morera Brenes, Bernal
Barrantes Mes?n, Ramiro
Mar?n Rojas, Rafael
author_sort Morera Brenes, Bernal
title Gene admixture in the Costa Rican population
title_short Gene admixture in the Costa Rican population
title_full Gene admixture in the Costa Rican population
title_fullStr Gene admixture in the Costa Rican population
title_full_unstemmed Gene admixture in the Costa Rican population
title_sort gene admixture in the costa rican population
publisher Ann Hum Genet; 67 (1) p. 71-80
publishDate 2015
url http://onlinelibrary.wiley.com/doi/10.1046/j.1469-1809.2003.00010.x/epdf
http://hdl.handle.net/10669/11386
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